标性肥胖与良性前列腺增生/下尿道症状的关联:全国横截面研究
Zhonghan Zhou1,2, Gongyue Liu1,2, Junjie Ji1,2
1School of Rehabilitation of Capital Medical University, China Rehabilitation Research Center, China Rehabilitation Science Institute, Beijing, China.
European urology open science
|November 11, 2025
概括
肌肉损失和肥胖的结合,标记性肥胖症显著增加了老年男性良性前列腺增生 (BPH) 和下泌尿道症状 (LUTS) 的风险. 管理这两种情况对于降低BPH/LUTS风险至关重要.
科学领域:
- 老年学是指老年学的学科.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢健康 代谢健康
背景情况:
- 良性前列腺增生 (BPH) 和下泌尿道症状 (LUTS) 在老年男性中很常见.
- 麻症 (与年龄相关的肌肉质量损失) 和肥胖是老年人中普遍存在的疾病.
- 麻症和肥胖症 (麻性肥胖症) 对BPH/LUTS风险的综合影响尚不清楚.
研究的目的:
- 为了调查sarcopenia,肥胖和sarcopenic肥胖与BPH/LUTS之间的关联.
- 检查萨科佩尼亚和肥胖对BPH/LUTS风险的独立和联合影响.
主要方法:
- 2011年和2015年中国健康与退休长度研究 (CHARLS) 的数据分析.
- 将参与者 (年龄≥45岁) 分类为正常,肉,肥胖和肉性肥胖群体.
- 后勤回归模型用于评估身体组成和BPH/LUTS之间的关联和相互作用效应.
主要成果:
- 标本性肥胖与BPH/LUTS (17%) 的更高患病率显著相关.
- 在调整后,只有sarcopenic肥胖仍然与增加BPH/LUTS风险 (OR 1.51) 有关.
- 观察到沙尔科佩尼亚和肥胖之间存在显著的协同作用,导致风险增加40%.
结论:
- 在老年男性中,sarcopenic肥胖是BPH/LUTS的独立风险因素.
- 皮症和肥胖症的共存对BPH/LUTS风险具有协同作用.
- 建议采用全面的管理策略,应对石症和肥胖症,以减轻BPH/LUTS.
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