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Updated: Jan 11, 2026

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
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在老年患者中出现的第二次恶性瘤,这些老年患者患有与鲁克索利提尼布治疗的经典骨髓扩散性瘤

Rong Wang1,2, Jessica M Stempel2,3, Rory M Shallis2,3,4

  • 1Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT.

Blood neoplasia
|November 11, 2025
PubMed
概括

卢克索利提尼布 (RUX) 的使用并没有增加患有骨髓增殖性瘤 (MPNs) 的老年患者出现第二次原发性恶性瘤 (SMs) 的风险. 这项研究发现,RUX用户和非用户之间的SM发展没有显著差异.

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