在认知灵活性期间神经激活的共同特征与独特特征跨越限制性饮食障碍介绍
Adrienne L Romer1,2, Lauren Breithaupt3,4,5,6, Meghan Slattery5,7
1Department of Psychology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
The International journal of eating disorders
|November 11, 2025
概括
在神经性厌食症 (AN) 和非典型的AN (Atyp-AN) 中,认知控制不同. 神经性厌食症患者表现出脊侧前额皮层 (dlPFC) 激活的改变,这表明限制性饮食障碍中的独特神经模式.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知心理学 认知心理学
背景情况:
- 限制性饮食障碍 (EDs),包括神经性厌食症 (AN) 和非典型的AN (Atyp-AN),与认知刚性有关.
- 脊侧前额皮层 (dlPFC) 对于认知控制至关重要,但其在EDs中的作用尚未完全理解.
研究的目的:
- 调查dlPFC在认知灵活性任务中的激活在限制性ED表现中的差异.
- 探索dlPFC激活和ED症状之间的关联.
主要方法:
- 87名患有限制性EDS的女性在任务交换范式期间接受了功能磁共振成像 (fMRI).
- 在持续 (任务交换与单一任务) 和暂时控制 (规则交换与规则重复) 期间检查dlPFC激活.
主要成果:
- 与其他组相比,AN组表现出明显的左 dlPFC 激活模式,主要是由于单任务条件下激活减少.
- 在任务交换期间,在任务执行或dlPFC激活方面没有观察到群体差异.
- 在任务切换期间增加dlPFC激活与所有参与者的更大的克制症状有关.
结论:
- 研究结果揭示了限制性EDS认知控制的共同和独特的神经特征.
- 在暂时控制期间增加dlPFC激活可能是限制性EDS的跨诊断特征.
- 在典型的AN中持续控制期间改变dlPFC激活值值得考虑量身定制的干预措施.
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