相关实验视频
Updated: Jan 11, 2026

14:49
Conducting Respiratory Oscillometry in an Outpatient Setting
Published on: April 8, 2022
8.3K
高频振荡式通风与常规通风相比,对于在产期或近期出生的患有严重肺功能障碍的婴儿,高频振荡式通风相比
Nanthida Phattraprayoon1, Jacqueline J Ho2, Michelle Fiander3
1Princess Srisavangavadhana Faculty of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand.
The Cochrane database of systematic reviews
|November 11, 2025
概括
高频振荡通风 (HFOV) 对患有严重肺功能障碍的产后婴儿提供了比常规通风 (CV) 更不确定的好处. 有证据表明,HFOV可能会增加死亡率,需要进一步研究其有效性和安全性.
科学领域:
- 新生儿医学 新生儿医学
- 儿科肺病学 儿科肺病学
- 关键的护理关键的护理
背景情况:
- 肺部疾病是导致婴儿死亡的主要原因.
- 常规通风 (CV) 是婴儿呼吸衰竭的标准.
- 在CV的创新挑战了高频振荡通风 (HFOV) 的既定作用.
研究的目的:
- 为了比较HFOV与CV在患有严重肺功能障碍的终期/近期婴儿的疗效.
- 评估HFOV对该人口死亡率和发病率的影响.
- 更新关于这个主题的先前系统审查.
主要方法:
- 包括随机和准随机试验,比较HFOV和CV.
- 搜索了多个数据库,直到2024年5月.
- 通过元分析合成结果,并通过GRADE评估证据确定性.
主要成果:
- 其中包括3项涉及368名婴儿的研究.
- 关于治疗失败和肺空气泄漏的证据非常不确定.
- HFOV可能会增加死亡率,但证据的确定性很低.
结论:
- 目前的证据不足以支持或反驳HFOV在期/近期婴儿中的使用.
- 需要进一步进行高质量的RCT,重点关注神经发育结果.
- 对较新的CV模式和HFOV进行比较研究是有必要的.
相关概念视频
Mechanical Ventilation II: Invasive Ventilation
604
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
604
Mechanical Ventilation III: Noninvasive Ventilation
489
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
Noninvasive Positive-Pressure Ventilation...
489
Mechanical Ventilation I: Indication and Settings
2.5K
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
2.5K
Ventilatory Modes
1.3K
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
1.3K
Assessment of Ventilation II: Respiratory Depth and Rhythm
2.4K
Respiratory Depth
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
2.4K
Factors Affecting Pulmonary Ventilation
2.8K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
2.8K

