机器学习与胎儿体重估计的传统公式相比:一项国际多中心研究,评估出生体重百分点的预测准确性
Omer Dor1, Eran Ashwal2, May Cohen1
1Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
概括
与哈德洛克公式相比,机器学习 (ML) 模型,特别是LightGBM和XGBoost,显示出与哈德洛克公式相比,整体出生体重预测准确度有所提高. 然而,ML在识别百分位基胎儿风险方面提供了有限的收益.
科学领域:
- 围产儿医学 围产儿医学
- 医疗信息学 医疗信息学
- 计算生物学 计算生物学
背景情况:
- 哈德洛克公式是目前用于估计胎儿体重的临床标准.
- 尽管有现有模型,但需要提高出生体重预测的准确性.
研究的目的:
- 评估机器学习 (ML) 模型是否可以提高出生体重预测的准确性.
- 将各种ML模型的性能与已确定的哈德洛克公式进行比较.
主要方法:
- 一个多中心的回顾性研究包括9674个单子怀孕.
- 使用超声波和母体数据训练了ML模型 (线性回归,决策树,随机森林,LightGBM,XGBoost,神经网络).
- 性能指标包括平均绝对百分比误差 (MAPE),RMSE,MAE,准确性,精度,回忆和F1分数.
主要成果:
- 与哈德洛克公式 (MAPE ~0.065) 相比,LightGBM和XGBoost的整体重量估计准确度更高.
- ML模型显示出出生体重百分点 (<3,<10,>90,>97) 的边际或可比改善.
- 轻GBM在极端百分位数中获得了更高的准确性和F1得分,而Hadlock在特定情况下的回忆略好一些.
结论:
- 机器学习模型,特别是LightGBM和XGBoost,显著改善了整体胎儿体重预测.
- 使用ML识别百分位基胎儿风险的收益有限.
- 哈德洛克公式仍然是一个有价值的工具来分类风险胎儿.
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