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Updated: Jan 11, 2026

Capturing Common Fragile Site Breaks by Native γH2A.X ChIP
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死亡盒螺旋酶gcDDX56破坏IRF3核进口复合体,并促进核IRF3降解,以增强GCRV复制

Li Li Xiao1,2, Yang Chen2, Jie Zhang2

  • 1College of Life Science, Hunan Normal University, Changsha, China.

Journal of virology
|November 11, 2025
PubMed
概括

草DDX56 (gcDDX56) 通过自降解IRF3并通过隔离importin β3 (gcKPNB3) 阻止其核进口来抑制抗病毒免疫力. 这种特异性的机理为GCRV感染和潜在的水产养殖疾病控制策略提供了洞察力.

关键词:
在 IRF3 中,IRF3 是 IRF3 的一个类型.KPNB3KPNB3KPNB3KPNB3KPNB3KPNB3KPNB3KPNB3KPNB3KPNB3KPNB3KPNB3草鱼 DDX5656 在这里.草地鱼的reovirus是一种病毒.

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