关于RCH2F和RCHF2基因中不适当的结的性质

Bruno A Piscelli1,2, Michael Bühl2, Rodrigo A Cormanich1

  • 1University of Campinas, Chemistry Institute, Monteiro Lobato Street, Campinas, Sao Paulo, 13083-862, Brazil.

概括

像RCH2F和RCHF2这样的化基团通过改变水的亲和力来影响药物特性. 计算研究显示,与离子的静电相互作用,而不仅仅是键,主导着它们的行为.

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