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通过通过β-arrestin1/STAT3通路抑制NF-κB激活,IGF-1可以预防急性胰腺炎

Xiaoli Huang1,2,3, Li Tao1,2,3, Huiling Liu1,2,3

  • 1Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, 510630, Guangdong, P. R. China.

Molecular and cellular biochemistry
|November 11, 2025
PubMed
概括

胰岛素样生长因子-1 (IGF-1) 通过调节β-arrestin-1/STAT3通路并抑制NF-κB激活,显示出对急性胰腺炎 (AP) 的保护作用. 这一发现为AP提供了新的治疗点.

关键词:
在IGF-1的基础上,IGF-1在 NF-κBB 中.胰腺炎是一种胰腺炎.在STAT3中,我们可以使用STAT3.这是一种β-arrestin.

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