蜂蜜微生物群中的益生菌Apilactobacillus Kunkeei EABW06:功能性乳制品食品的候选者
Mariam Hassan1,2, Yasser Essam Elenany3, Ashwak Abdel-Moneim Hassan4
1Department of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo, 11562, Egypt. mariam.hassan@pharma.cu.edu.eg.
Probiotics and antimicrobial proteins
|November 11, 2025
概括
蜜蜂细菌Apilactobacillus kunkeei EABW06显示出强大的益生菌潜力. 它在消化过程中存活下来,与病原体作斗争,并在食品生物技术中有应用.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 生物技术是生物技术.
背景情况:
- 蜂菌 (Apilactobacillus kunkeei) 是一种来自蜜蜂微生物群的果性乳酸细菌 (FLAB).
- 它正在作为一种非常规的益生菌来源引起人们的注意.
研究的目的:
- 评估A. kunkeei EABW06.06的益生菌,安全性和技术性质.
- 评估其对人类和生物技术应用的潜力.
主要方法:
- 评估胃肠道弹性 (pH,胆盐).
- 对细菌和真菌进行评估的抗微生物活性.
- 使用HPLC分析的主导代谢物.
- 进行了安全评估 (血液溶解,细胞毒性,抗生素敏感性).
- 进行了牛奶发酵试验,以评估技术特性.
主要成果:
- A. kunkeei EABW06在pH值为3.0时显示>96%的存活率和对胆汁盐的耐受性.
- 已经证明对大肠杆菌O157:H7,S. typhi,C. difficile,A. fumigatus,A. flavus和C. albicans的广泛抗菌活性.
- 在HPLC中,乙酸,乳酸,黄油酸和酸是主要代谢物.
- 安全性评估证实没有血液溶解,非细胞毒性和抗生素敏感性.
- 牛奶发酵导致pH值降至4.5,0.98%的乳酸产生,以及蛋白质分解活性.
结论:
- A. kunkeei EABW06是一种安全而强大的益生菌候选者.
- 它具有生物保存和乳制品生物技术应用的巨大潜力.
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