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Updated: Jan 11, 2026

Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils
15:04

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基于西利马林的纳米薄膜有效地保护线粒体免受由α-Synuclein Amyloid 聚合物介导的氧化损伤

Zahra Mahmoudi Eshkaftaki1, Saeed Emadi1, Ali Akbar Meratan1

  • 1Department of Biological Sciences, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan 45137-66731, Iran.

ACS chemical neuroscience
|November 11, 2025
PubMed
概括

西利马林 (SIL) 是一种天然化合物,可以保护线粒体免受阿尔法-同核素 (α-syn) 聚合物造成的损伤,这是帕金森病 (PD) 的关键因素. SIL纳米片显示出对这种线粒体功能障碍的优越保护作用.

关键词:
氨基化物 氨基化物线粒体中的线粒体.纳米化的纳米化.氧化损伤是因为氧化损伤.西利玛林是一种制剂.α-synuclein 是一种同核蛋白.

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