在中年和老年人中,热逆转和认知轨迹之间的关联在CHARLS:一个潜在的类轨迹分析中
Kai Liu1, Jing Wang1, Junru Wang1
1Department of Epidemiology and Health Statistics, School of public health, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, China.
PloS one
|November 11, 2025
概括
更高的热反转 (TI) 暴露与45岁以上成年人的认知轨迹恶化有关. 减少TI可能会支持更健康的认知衰老,并预防认知衰退.
科学领域:
- 环境健康 环境健康
- 神经科学是一个神经科学.
- 老年学是一门学科.
背景情况:
- 认知能力下降与气象条件有关,但热逆转 (TI) 的影响仍未得到充分研究.
- 现有的研究主要集中在空气污染物,在了解TI对认知功能的影响方面存在差距.
研究的目的:
- 调查热逆转 (TI) 暴露和认知功能轨迹之间的关联.
- 探索TI在认知发展和随着时间的推移而下降的模式中的作用.
主要方法:
- 利用了中国健康与退休长度研究 (2011-2015年) 中5,762名参与者 (年龄45岁以上) 的数据.
- 采用隐性类轨迹建模 (LCTM) 来识别认知发展轨迹.
- 使用NASA的MERRA-2数据集评估TI,并通过多项逻辑回归和受限立方线分析其与认知轨迹的关系.
主要成果:
- 确定了三个不同的认知轨迹:U形,缓慢衰退和N形.
- 发现缓慢下降轨迹中较高比例的个体暴露于中度和高水平的TI.
- 与U形轨迹相比,更高的TI暴露显著增加了属于缓慢下降轨迹的几率 (中等OR=1.269,高暴露OR=1.478).
结论:
- 增加的热反转 (TI) 暴露与较差的认知轨迹有关.
- 旨在减少TI暴露的策略可能有助于保持更健康的认知衰老.
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