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CSF1R-CAR T细胞诱导CSF1R信号,并可以促进细胞的增殖

Aurora Callahan1, Xinyan Zhang2, Amber Wang1

  • 1Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, RI 02903, USA.

Science signaling
|November 11, 2025
PubMed
概括

化学抗原受体 (CAR) T细胞疗法可以触发目标癌细胞中的意外信号. 这项研究揭示了殖民地刺激因子1受体 (CSF1R) CAR T细胞诱导CSF1R信号,影响瘤细胞增殖.

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