印度空气污染对怀孕和早期儿童发育 (APiPED) 的影响:一个队列研究的协议
Harshal Ramesh Salve1,2, Sagnik Dey2,3,4, Yashika Arora1
1Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi, Delhi, India.
JMIR research protocols
|November 11, 2025
概括
这项研究考察了空气污染对印度怀孕和儿童发育的影响. 调查结果将为高污染地区的母亲和儿童健康政策提供信息.
科学领域:
- 环境健康 环境健康
- 母婴健康 母婴健康
- 发育儿科 发育儿科
背景情况:
- 关于空气污染对印度等高污染地区儿童早期发育的影响的证据有限.
- 了解这些影响对于人口密集,污染地区的公共卫生至关重要.
研究的目的:
- 调查空气污染对德里国家首都地区怀孕结果和早期儿童发展的影响.
- 为污染环境提供有针对性的干预措施和公共卫生政策提供证据.
主要方法:
- 在德里,对2500名孕妇及其2岁以下的孩子进行了纵向母婴队列研究.
- 收集母亲,新生儿和儿童发育数据,包括对空气污染暴露的监测 (PM2.5,PM10) 进行子样本.
- 用多变量回归和混合效应模型分析生物标志物和健康结果.
主要成果:
- 截至2025年7月,招聘工作已完成45%,收集了基线数据.
- 对于10%的队列,正在进行暴露评估和采样.
- 正在进行的数据收集和分析预计将产生重大发现.
结论:
- 该研究将全面评估空气污染对印度城市和农村环境中的孕产妇健康,怀孕和儿童发育的影响.
- 结果将为卫生政策和缓解策略提供关键的,特定于环境的证据.
- 研究结果将支持污染环境中的弱势群体的个人保护措施.
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