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Updated: Jan 11, 2026

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
05:17

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451

Published on: April 18, 2025

781

作为潜在的针对阿尔茨海默氏症疾病的多目标化合物的pyranotacrines

Salma Fares1, Walaa M El Husseiny1, Khalid B Selim1

  • 1Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.

Bioorganic & medicinal chemistry
|November 11, 2025
PubMed
概括

一种新的基于塔克林的化合物6c通过抑制关键酶和减少β-粉样蛋白聚合,显示出对阿尔茨海默病的强有力的多目标活性. 这种有前途的药物还具有抗氧化特性和良好的安全性.

关键词:
4-H-pyran是什么? 4-H-pyran是什么? 4-H-pyran是什么? 4-H-pyran是什么?通过ACHE抑制,可以抑制AChE.阿尔茨海默病的疾病阿尔茨海默病的疾病.抗氧化剂是一种抗氧化剂.抑制了Aβ聚合的抑制.在 BuChE 抑制过程中,通道封锁 通道封锁在这里,我们可以看到MTDL,MTDL.金属化 化金属化分子建模模拟的模拟.塔克里因是指一个神经元.

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