用扩展的有限元素方法分析老年骨高原骨折的内在贡献因素的分析
Yafeng Li1, Bopeng Zhang1, Fengyuan Lu1
1School of Mechanical Engineering, Tiangong University, Tianjin 300387, China; Tianjin Key Laboratory of Advanced Mechatronics Equipment Technology, Tiangong University, Tianjin 300387, China.
Journal of biomechanics
|November 11, 2025
概括
老化骨密度,而不仅仅是结构,显著影响骨平原骨折的风险. 脊椎骨密度降低是最大的威胁,特别是在女性中,增加他们的骨折易受性.
科学领域:
- 整形外科 整形外科 整形外科
- 生物力学 生物力学
- 老年学是一门学科.
背景情况:
- 目前的骨折风险评估严重依赖骨矿物质密度 (BMD),经常忽视与年龄相关的骨结构退化.
- 老龄化过程中的骨质损失损害了骨结构的机械完整性,例如骨高原.
研究的目的:
- 研究皮质骨厚度 (Ct.Th),皮质骨矿物质密度 (Ct.BMD),轨道骨体积分数 (BV/TV) 和轨道骨矿物质密度 (Tb.BMD) 与年龄相关的变化如何影响平原承载能力.
- 为了比较骨密度下降与结构退化的影响,骨平原在衰老中的机械功能.
- 分析与年龄相关的骨变化中的基于性别的差异及其对骨平原骨折风险的影响.
主要方法:
- 开发一种扩展有限元法 (XFEM) 模型,用于模拟骨高原骨折.
- 使用复合骨机械测试数据和尸体测试结果验证XFEM模型的验证.
- 对不同Ct.Th,Ct.BMD,BV/TV和Tb.BMD对高原承载能力的机械影响的分析.
主要成果:
- 在衰老过程中,椎骨密度的降低对部平原承载能力产生了最显著的负面影响.
- 骨密度的下降对承载能力的影响比结构性退化 (Ct.Th,BV/TV) 更大.
- 与男性相比,女性的基线水平较低,关键骨因子的下降速度较快,导致负载能力降低,并在相似年龄增加骨折风险.
结论:
- 骨密度,特别是骨密度,在衰老过程中是高原承载能力的关键决定因素,而不是结构参数.
- 与年龄相关的骨密度下降显著增加了小腿高原骨折的风险,女性更容易受到伤害.
- 考虑骨密度和结构变化的多因素方法对于准确预测老年人高原骨折风险至关重要.
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