在PICU退院后12个月内使用验证的查工具进行功能性发病率
Debra J Rosenbaum1, Nori M Minich2,3, Rajashri Rasal2
1Department of Anesthesiology Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, California.
Hospital pediatrics
|November 11, 2025
概括
儿科重症监护室 (PICU) 的幸存者面临获得的功能障碍,其中13%的人在出院后一个月受到影响. 侵入性机械通风 (IMV) 显著增加了这种风险,许多儿童在一年内无法完全康复.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 神经发育结果的神经发育结果
- 儿科重症监护室 (PICU) 的研究.
背景情况:
- 严重疾病后获得的功能障碍会影响儿童的发育.
- 了解患病率,发展轨迹和风险因素对于早期干预至关重要.
- 经过验证的查工具对于准确的评估至关重要.
研究的目的:
- 描述PICU出院后儿童中获得性功能障碍的患病率和发展轨迹.
- 与疾病前状态相比,识别与获得性功能障碍相关的风险因素.
- 用适合年龄的,经过验证的查工具进行全面评估.
主要方法:
- 对1个月至17岁的儿童进行前性单中心研究,这些儿童被录入PICU.
- 使用经过验证的工具评估疾病前基线发育状况.
- 在PICU退院后的1,6个月和12个月进行后续评估.
主要成果:
- 13%的儿童在出院1个月后表现出获得的功能障碍.
- 侵入性机械通风 (IMV) 是一个显著的风险因素 (OR 2.72).
- 35%的患者在最后一次评估时表现出持续的获得性功能障碍.
结论:
- 大约八分之一的儿童在PICU出院后经历了获得的功能障碍.
- 接受IMV治疗的儿童患上获得性功能障碍的风险要高得多.
- 大多数儿童在PICU后6-12个月内不会完全恢复基线功能.
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