[慢性咳:是时候认识到它是一种疾病]
1Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China.
概括
持续超过8周的慢性咳越来越多地被视为一种具有各种表型的独特疾病,例如无法解释的慢性咳. 承认它是一种疾病实体有助于诊断,研究和患者护理.
科学领域:
- 肺部病理学 肺部病理学
- 临床医学 临床医学
- 病理生理学 病理生理学
背景情况:
- 慢性咳在临床上被定义为持续超过8周的咳,没有胸部X射线异常.
- 新出现的证据表明慢性咳是一种具有多种表型的疾病,通常涉及咳过敏.
- 无法解释或不耐药的慢性咳代表了一个特定的,独特的表型.
研究的目的:
- 倡导将慢性咳定义为一个独立的疾病实体.
- 强调将重点从症状管理转移到疾病管理的好处.
- 强调临床实践和研究的潜在改进.
主要方法:
- 审查当前的临床定义和新出现的证据.
- 对慢性咳表型的病理生理方面的分析.
- 讨论重新分类慢性咳的含义.
主要成果:
- 慢性咳表现出多种现象,包括咳过敏.
- 无法解释的慢性咳 (UCC) 和耐火性慢性咳 (RCC) 是已知的表型.
- 将慢性咳重新归类为一种疾病实体提供了显著的优势.
结论:
- 将慢性咳定义为一个独特的疾病实体,标准化了诊断和流行病学.
- 这一转变改善了医疗教育,保险报销和医生与患者的沟通.
- 它还减少了不必要的干预,并促进了慢性咳病原和治疗方法的研究.
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