饮食引起的炎症与健康结果之间的关联:基于人口的全现象关联研究研究
Weiwei Chen1,2, Ke Liu1, Xinzhe Jing1
1School of Public Health, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
NPJ science of food
|November 11, 2025
概括
饮食炎症指数 (DII) 与许多健康结果有关,特别是在消化,循环和代谢系统. 采用抗炎饮食可能有助于预防与较高DII相关的疾病.
科学领域:
- 营养科学 营养科学
- 遗传学 遗传学 是一个
- 流行病学 流行病学
背景情况:
- 将饮食炎症指数 (DII) 与健康结果联系在一起的证据是不一致的.
- 需要对DII对各种健康结果的影响进行全面评估.
研究的目的:
- 评估DII与广泛的健康结果之间的关联.
- 通过使用孟德尔随机化来研究DII对健康的因果关系.
主要方法:
- 对845个健康结果的全现象关联分析与DII.II.
- 孟德尔随机化 (MR) 分析使用遗传仪器 rs7910002.
- 用两个样本的MR来确认与特定疾病的关联.
主要成果:
- 133个健康结果与DII显著相关 (PFDR <0.05).
- MR确定了25个与DII相关的健康结果,其中7个显示一致的效果.
- 较高的DII增加了腹,胆病和背部疼痛的风险.
结论:
- DII与多个身体系统的众多健康结果有关.
- 门德尔随机化支持高DII和特定条件之间的因果关系.
- 促进抗炎饮食对于预防疾病至关重要.
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