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Updated: Jan 11, 2026

Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance SPR
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在IV型多药ABC输送器中,核酸和基质结合点之间的双向通信

Victor Hugo Pérez Carrillo1, Margot Di Cesare2, Dania Rose-Sperling1

  • 1Faculty of Chemistry and Earth Sciences, Institute of Organic Chemistry and Macromolecular Chemistry, Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.

Nature communications
|November 11, 2025
PubMed
概括

研究人员在IV型ABC输送器中确定了一个关键的残留集群,该集群作为通信关. 这条链对于协调多药耐药中的ATP水解与基质运输至关重要.

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