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Updated: Jan 11, 2026

Ultra-long Read Sequencing for Whole Genomic DNA Analysis
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Ultra-long Read Sequencing for Whole Genomic DNA Analysis

Published on: March 15, 2019

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长读序列化解异形复杂性在异位基因特定的位置

Lison Lemoine1,2, Sarah Hoelzl1,2, Tim P Hasenbein1,2

  • 1Institute of Pharmacology and Toxicology, Technical University of Munich, Munich, Germany.

Scientific reports
|November 11, 2025
PubMed
概括

长读测序准确地映射复杂的等位基因特定位置上的转录异型. 这种新的方法,结合了Iso-Seq和WhatsHap分相,揭示了异位基因特异性的基因表达和小鼠的印记模式.

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G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

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RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
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