男性的侵袭性前乳腺瘤与视觉障碍和垂体激素缺陷有关
Everardo J Díaz-López1,2, Rocío Villar-Taibo3, Eva Fernández-Rodríguez4
1Department of Endocrinology and Nutrition , University Clinical Hospital of Santiago de Compostela , Compostela , Spain. everardodiaz2@gmail.com.
Scientific reports
|November 11, 2025
概括
男性的侵袭性前乳腺瘤往往伴有视力障碍和荷尔蒙缺乏. 诊断时血清激素水平升高和瘤大小可能表明有侵略性的垂体瘤.
科学领域:
- 内分泌学 在内分泌学.
- 神经瘤学神经瘤学
- 在瘤学瘤学.
背景情况:
- 益生菌瘤 (乳腺垂体神经内分泌瘤) 在男性中很罕见,其特征不太清楚.
- 世界卫生组织将前乳腺瘤分类为具有高复发风险的瘤.
- 识别男性侵略性前性腺瘤的临床指标对于及时干预至关重要.
研究的目的:
- 为了确定临床参数,暗示男性群体中具有侵略性的前性乳腺瘤.
- 分析临床表现和瘤攻击性之间的关系.
主要方法:
- 在西班牙加利西亚的三个医院进行了一项回顾性研究.
- 分析了41名被诊断患有前性腺瘤的男性患者的数据.
- 在攻击性和非攻击性瘤组之间比较了诊断时的临床参数.
主要成果:
- 侵袭性前乳腺瘤 (24%的病例) 与较高的视力障碍率 (60%vs. 13%) 和甲状腺刺激激素 (70%vs. 13%) 和上腺皮质激素 (50%vs. 7%) 的缺陷有关.
- 增加的益生素水平与瘤直径相关,在侵袭性病例中观察到更强的相关性 (r=0.68).
- 巨型乳腺瘤占95%的病例,诊断时的平均年龄为46.5岁.
结论:
- 男性的前性腺瘤经常出现显著升高的前性腺素水平和更大的瘤直径.
- 视觉障碍和TSH和ACTH缺乏症等临床症状应引起对侵袭性垂体瘤的怀疑.
- 这些发现有助于早期检测和管理男性的侵袭性前性腺瘤.
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