COVID和MIS-C对儿童的神经和神经发育的影响
D Byrne1,2,3, C Gale4,5, N Canty2
1Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Pediatric research
|November 11, 2025
概括
严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 可能会在儿童中引起独特的神经症状. 更多的研究对于了解SARS-CoV-2的长期神经和神经发育影响以及儿科人口中相关的炎症综合征至关重要.
科学领域:
- 儿科神经学 儿科神经学
- 传染性疾病 传染性疾病
- 神经发育障碍 神经发育障碍
背景情况:
- 儿科人口表现出来自SARS-CoV-2的独特疾病表型,包括儿童多系统炎症综合征 (MIS-C) 和PIMS-TS.
- 在感染SARS-CoV-2的儿童中,越来越多地报告了神经症状.
- 在儿童中,SARS-CoV-2感染和MIS-C/PIMS-TS的长期神经和神经发育后果仍然不太清楚.
研究的目的:
- 审查有关SARS-CoV-2和MIS-C在儿童的神经和神经发育影响的当前知识.
- 强调SARS-CoV-2和MIS-C对儿科患者神经和神经发育结果的潜在直接影响.
- 强调需要进一步研究SARS-CoV-2的病理生理学和神经病毒性.
主要方法:
- 关于SARS-CoV-2的儿科神经学后果研究的综合文献综述.
- 对与急性SARS-CoV-2感染和MIS-C/PIMS-TS.TS相关的神经症状报告病例的分析.
- 综合当前关于受影响儿童神经发育结果的理解.
主要成果:
- 神经症状是SARS-CoV-2在儿童中已知的表现.
- MIS-C/PIMS-TS可能会出现显著的神经和神经发育并发症.
- 在儿童群体中SARS-CoV-2的直接神经毒性需要进一步调查.
结论:
- 承认SARS-CoV-2和MIS-C的潜在直接神经影响对于儿科护理至关重要.
- 长期后续研究对于充分了解儿童神经发育后续是必不可少的.
- 需要更多的研究来阐明与SARS-CoV-2相关的神经疾病的机制.
更多相关视频
09:39Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult
Published on: April 26, 2018
9.1K
07:13Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
Published on: March 25, 2016
19.5K
相关概念视频
01:28Disorders of the Nervous Tissue
2.5K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
2.5K
01:30Attention-Deficit/Hyperactivity Disorder
725
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
725
01:27Language and Cognition
700
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
700