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Updated: Jan 11, 2026

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RNF220调解了STAT3的K63相关的多基化,并加剧了病理性心脏缩

Yan Gao1,2,3, Zhuo Zhao3, Xuepin Chen1,2

  • 1Department of Cardiology, Qingdao University, Qingdao, 266071, China.

Cell death and differentiation
|November 11, 2025
PubMed
概括

环指蛋白220 (RNF220) 通过稳定STAT3蛋白来调节病态心脏缩. 缺少RNF220可以防止心脏膨胀,而过度表达会恶化心脏功能障碍,从而成为心脏衰竭的治疗点.

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