更大的前额叶皮层激活与老年人更高的平衡信心有关
Jin-Young Min1, Baek-Yong Choi2, Seung-Woo Ryoo2
1Veterans Health Service Medical Center, Veterans Medical Research Institute, Seoul, Republic of Korea.
GeroScience
|November 11, 2025
概括
老年人对跌倒的恐惧与大脑活动有关. 较大的前额叶皮层激活与更好的平衡信心相关,特别是那些有跌倒史的人.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 认知心理学 认知心理学
背景情况:
- 恐惧跌倒 (FoF) 显著影响老年人的移动性和生活质量.
- 越来越多的FOF被视为与认知运动控制有关的神经行为问题,而不仅仅是心理困扰.
- 前额叶皮层 (PFC),对于执行功能至关重要,涉及到FoF.
研究的目的:
- 研究前额叶皮层 (PFC) 激活和老年人平衡信心之间的关系.
- 探索通过fNIRS测量前额氧化血红蛋白 (HbO) 的PFC活性与活动特异平衡信心 (ABC) 度数如何相关.
- 检查秋季史,年龄,性别和教育对这种关联的潜在缓解影响.
主要方法:
- 功能近红外谱学 (fNIRS) 在308名年龄≥60岁的成年人口语流利任务中测量了前额头HbO.
- 资产负债表信心被评估使用韩国版本的特定活动资产负债表信心 (ABC) 尺度.
- 进行了统计分析,包括子组分析,以确定关联和潜在异质性.
主要成果:
- 较高的前额前部HbO水平与较高的ABC分数显著相关,表明更高的平衡信心和较低的FoF.
- 该协会在右侧和下PFC区域最突出.
- 较强的关联在下降史,年龄较大 (≥75岁),女性和教育程度较低的子组中观察到.
结论:
- 增加PFC激活与老年人更强的平衡信心有关.
- 这种关系表明适应性皮层参与可能支持姿势稳定性,特别是在脆弱人群中.
- 研究结果突出了FoF的神经生物学基础及其由认知因素的潜在调节.
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