障碍和认知衰退之间的双向关系:一项为期6年的纵向研究
Tsung-Hsuan Hung1, Tzu-Yun Wang2, Hung-Chang Chou3
1Department of Medical Education, Kaohsiung Chang Gung Memorial Hospital, No.123, Dapi Rd, Niaosong District, Kaohsiung, 833, Taiwan.
BMC geriatrics
|November 11, 2025
概括
老年人的残疾和认知障碍是双向联系在一起的. 然而,残疾显著影响未来的认知衰退,而不是认知影响未来的残疾.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 老龄化与残疾和认知障碍的风险增加有关.
- 了解这些条件之间的相互作用对于有效的干预至关重要.
研究的目的:
- 调查老年人的残疾和认知障碍之间的双向关系.
- 为了确定哪一个因素,残疾或认知障碍,随着时间的推移对另一个因素有更大的影响.
主要方法:
- 对来自社会环境和衰老生物标志物研究 (SEBAS) 的628名参与者的纵向分析.
- 使用修改后的简短便携式精神状态问卷 (SPMSQ) 评估认知功能.
- 通过日常生活活动,日常生活的工具活动和移动性尺度来衡量残疾,使用结构方程模型进行交叉滞后分析进行分析.
主要成果:
- 交叉滞后模型表明,在6年内,残疾和认知功能之间存在显著的双向关系.
- 基线残疾显著预测了未来的认知障碍 (β=-0.25,p < 0.05).
- 基线认知功能也预测了未来的残疾 (β=-0.03,p < 0.05),但从残疾到认知障碍的途径更强 (费舍尔的Z测试,p < 0.001).
结论:
- 在老年人群中,残疾和认知功能表现出双向关系.
- 障碍似乎对随后的认知障碍产生更大的影响.
- 建议进一步研究这种关系背后的机制.
更多相关视频
08:43Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
Published on: August 7, 2017
8.3K
07:42Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
Published on: December 16, 2022
3.6K
相关概念视频
Language and Cognition
676
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
676
Cognitive Development During Adulthood
737
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
737
Intellectual Disability
580
Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
580
Longitudinal Research
13.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.0K
Relationship Formation
45.2K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
45.2K
Learning Disabilities
541
Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...
Dyslexia
Dyslexia is a...
541
