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螺旋体积调制弧线疗法用于全脑放射治疗,同时整合促进多个大脑转移

Yuan Xu¹, Junjie Miao², Jianrong Dai³

¹Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.

Radiation oncology (London, England)

|November 11, 2025

概括

螺旋体积调制弧线疗法 (SVMAT) 与螺旋式断层疗法相比,为全脑放射疗法提供了更好的计划质量和更高的输送效率,同时提供了综合增强. SVMAT显示的计划质量与 VMAT 的计划质量相当,增强了多重脑转移的治疗选择.

科学领域:

辐射瘤学辐射瘤学
医学物理医学物理

背景情况:

螺旋体积调制弧线疗法 (SVMAT) 集成体积调制弧线疗法 (VMAT) 和螺旋式断层疗法 (HT) 的原则.
SVMAT利用纵向沙发运动来实现螺旋/螺旋式辐射输送轨迹.
这种技术旨在结合VMAT和HT的优势.

研究的目的:

评估SVMAT对全脑放射疗法 (WBRT) 与同时集成增强 (SIB) 的治疗计划.
评估SVMAT在治疗大量大脑转移 (> 40) 的疗效.
为了比较SVMAT计划质量和交付效率与HT和零碎VMAT (PVMAT).

主要方法:

对10名患有40-120个大脑转移的患者的回顾性分析,这些患者先前接受过HT治疗.
在NeuRT Aurora放射治疗机上使用DeepPlan软件生成SVMAT计划.
计划使用20度计划质量指标 (PQM) 进行比较,评估目标覆盖范围,危险器官节省和光束交付时间.

主要成果:

SVMAT证明了与HT和PVMAT相比的目标覆盖率和符合性.
与HT相比,SVMAT观察到右海马,视神经和视觉的显著改善.
在SVMAT计划中,PQM得分高于HT,得分与PVMAT相当.
与HT和PVMAT相比,SVMAT的光束传递时间更短 (特别是6次旋转).

结论:

与WBRT + SIB的HT相比,SVMAT提供了优越的计划质量和交付效率.
SVMAT 的计划质量与 PVMAT 的计划质量相似.
SVMAT代表了治疗WBRT + SIB广泛的大脑转移的有希望的进展.

关键词:

大脑转移是大脑的转移.螺旋式断层疗法螺旋式断层疗法同时的集成提升.螺旋体积调节弧疗法螺旋体积调节弧疗法全脑放射疗法全脑放射疗法

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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).