双相情绪障碍成年人的坚持障碍,自我报告的坚持和精神症状之间的关联
Martha Sajatovic1,2, Jennifer B Levin1,2, Clara Adeniyi1
1Department of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Bipolar disorders
|November 12, 2025
概括
患有双相情感障碍 (BD) 的个人在药物坚持方面扎,表现出更严重的情绪症状. 关键障碍包括生活方式和物质使用,强调需要有针对性的干预措施来改善坚持.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 低于最佳的药物坚持是双相情感障碍 (BD) 患者面临的重大挑战.
- 了解个体特征和与坚持水平相关的特定障碍至关重要.
- 本研究介绍了一项正在进行的随机对照试验 (RCT) 的临时发现.
研究的目的:
- 检查患者报告的坚持,坚持障碍和BD患者情绪症状之间的关联.
- 确定导致BD患者药物不服药的特定因素.
- 为制定有针对性的干预措施提供信息,以改善BD的遵守.
主要方法:
- 对129名参与者进行了一项RCT的临时分析,该RCT涉及患有BD类型1或2的成年人 (≥18岁).
- 参与者表现出积极的症状,并对药物坚持有困难.
- 使用平板电脑常规问卷 (TRQ) 测量了坚持,使用牛津双极知识问卷 (OBQ),自我报告习惯指数 (SRHI),沟通风格尺度 (CSS) 和变化准备和治疗热情尺度 (SOCRATES 8A) 评估了障碍.
主要成果:
- 在查和基线时,患有BD的不良依附个体在蒙哥马利阿斯伯格抑郁评分表 (MADRS) 和简短精神病评分表 (BPRS) 上表现出显著更高的得分.
- 自我报告习惯指数 (SRHI) 与查和基线时的TRQ相反相关.
- 苏格拉底8A (采取步骤子规模) 也与基线的TRQ相反相关.
结论:
- 患有BD的个体经历了不良的坚持,出现了更严重的全球精神病理和抑郁症状.
- 已识别的坚持障碍包括阻碍定期服用药物的生活方式,以及减少物质使用的挑战.
- 促进遵守的努力应集中在具体的,可采取行动的障碍,以有效地管理BD.
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