牙周炎和牙脱落与更高的认知障碍风险有关:一个系统的雨元分析
Balen Hamid Qadir1, Mohammed Khalid Mahmood2, Yad Mariwan Mohammed Amin3
1Department of Dentistry, Komar University of Science and Technology, Sulaymaniyah, Kurdistan, Iraq.
Clinical and experimental dental research
|November 12, 2025
概括
牙周病 (PD) 与老年人认知障碍 (CD) 的风险更高有关. 这一总体元分析证实了PD与CD发育之间存在显著的关联.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 口腔健康 口腔健康
背景情况:
- 牙周病 (PD) 和认知障碍 (CD) 是老年人群中普遍存在的疾病.
- 新出现的证据表明,口腔健康和认知功能之间存在潜在联系.
研究的目的:
- 进行一项总体元分析,评估牙周病与认知障碍之间的关联.
- 综合现有元分析的发现,以提供有关关系的全面概述.
主要方法:
- 在PubMed和MEDLINE数据库中搜索到2025年6月之前的相关元分析.
- 使用的赔率比率 (OR) 和相对风险 (RR) 用于比较分析.
- 在最终的综合分析中包括了20个元分析.
主要成果:
- 患有PD的个体表现出患有或发展所有类型CD的几率增加 (OR = 1.65).
- 严重的牙周炎显示,认知障碍的风险明显更高 (OR = 2.69).
- 对队列研究的综合分析表明存在显著的相对风险 (RR = 1.26).
结论:
- 牙周病与认知障碍有关.
- 这种关联的证据确定性低至中等,以GRADE来衡量.
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