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Updated: Jan 11, 2026

Large-scale Top-down Proteomics Using Capillary Zone Electrophoresis Tandem Mass Spectrometry
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Large-scale Top-down Proteomics Using Capillary Zone Electrophoresis Tandem Mass Spectrometry

Published on: October 24, 2018

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蛋白质形式映射要求从底部向上和自上而下的蛋白质组学进行联合努力

Yuri E M van der Burgt1

  • 1Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.

Proteomics
|November 12, 2025
PubMed
概括

顶向下蛋白质组学 (TDP) 能够为精准医学提供详细的蛋白质形状映射. 这项研究比较了SDS去除方法,这对于强大的TDP样品制备和蛋白形分析至关重要.

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相关概念视频

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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