与美国的COPD和喘相比,由于支气管切除症住院的病例较多
Mohamad El Labban1, Alwatheq Al-Itelat2, Timothy R Aksamit2
1Department of Internal Medicine, Mayo Clinic Health System, Mankato, MN, USA.
ERJ open research
|November 12, 2025
概括
在美国,由于支气管切除症恶化而住院的结果比COPD和喘更糟糕. 支气管切除症患者经历了更长的停留时间,更高的成本和更高的死亡率,即使是在大流行期间.
科学领域:
- 肺部医学 肺部医学
- 医疗保健服务研究 医疗服务研究
- 流行病学 流行病学
背景情况:
- 支气管病,COPD和喘是具有明显临床轨迹的慢性呼吸道疾病.
- 了解住院结果的差异对于优化患者护理和资源配置至关重要.
- 之前的研究还没有全面比较这三个条件的住院结果.
研究的目的:
- 为了比较支气管切除症恶化的住院结果与慢性阻塞性肺病 (COPD) 和喘恶化的住院结果.
- 分析与这些住院相关的人口因素,并发症,成本,住院时间和死亡率.
- 评估SARS-CoV-2流行病对这些疾病住院发生率和死亡率的影响.
主要方法:
- 从2017年1月到2021年12月,对美国所有付款者数据库进行了回顾性分析.
- 包括由于支气管切除,COPD和喘恶化而住院的病例.
- 对人口统计数据,医院特征,并发病,费用,住院时间和死亡率进行统计分析,并对混因素进行调整.
主要成果:
- 支气管切除症队列 (n=232,825) 与COPD (4天,384040美元) 和喘 (3天,31262美元) 相比,平均住院时间更长 (5天) 和平均成本更高 (50,393美元).
- 经过调整的分析显示,支气管切除症住院的死亡率是COPD的1.2倍,是喘的3.0倍 (p<0.0001).
- 在大流行期间 (2020-2021年),支气管切除症住院病例减少了8% (相比26%的COPD,28%的喘),而死亡率在所有群体中都上升. 重叠的疾病并没有增加死亡率.
结论:
- 与COPD和喘相比,美国的支气管切除症住院病例与明显更糟糕的结果有关.
- 这些结果包括更长的逗留时间,更高的医疗费用和更高的死亡率.
- 这些发现强调了针对支气管病变恶化需要有针对性的临床策略和资源管理的必要性.
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