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In the early 1900s, English chemist Frederick Soddy realized that an element could have atoms with different masses that were chemically indistinguishable. These different types are called isotopes — atoms of the same element that differ in mass. Isotopes differ in mass because they have different numbers of neutrons but are chemically identical because they have the same number of protons. Soddy was awarded the Nobel Prize in Chemistry in 1921 for this discovery.
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低收入和中等收入国家中的放射性疗法:挑战,实践和前景.

Ismaheel O Lawal1,2, Honest Ndlovu2,3, Joseph Kabunda2,3

  • 1Department of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia, United States.

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PubMed
概括

放射性治疗提供先进的癌症诊断和治疗,特别是在低收入和中等收入国家 (LMICs). 尽管在获取和基础设施方面存在挑战,但其改善LMIC癌症治疗的潜力是显著的.

关键词:
177 卢-PSMAMA 的时间225 阿克-PSMAMA 的情况.低收入和中等收入国家.核医学是核医学的一种.前列腺癌是前列腺癌.放射性其他无线电.

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科学领域:

  • 在瘤学瘤学.
  • 核医学就是核医学.
  • 无线电听器是一种无线电听器.

背景情况:

  • 全球癌症发病率和死亡率正在上升,低收入和中等收入国家 (LMICs) 被不成比例地影响.
  • 有效的癌症预防,早期诊断,治疗和生存策略对于低低收入国家至关重要.
  • 放射性疗法,将诊断成像和有针对性的治疗与放射性药物结合起来,显示了增强癌症管理的前景.

研究的目的:

  • 探索放射性射在解决LMIC中不断增长的癌症负担方面的潜力.
  • 确定阻碍在LMICs中采用核医学和放射性疗法的障碍.
  • 突出成功的应用和在LMICs中不断改进的辐射疗效服务.

主要方法:

  • 审查当前关于瘤学中放射性疗法应用的文献.
  • 分析LMIC在实施核医学服务方面面临的挑战.
  • 在LMICs成功实施放射性治疗的案例,特别是对于前列腺癌.

主要成果:

  • 放射性治疗提供敏感的功能成像,用于早期检测和治疗反应评估.
  • 在LMICs的主要障碍包括劳动力短缺,基础设施不足,资金有限和监管障碍.
  • 成功的临床应用,如用于前列腺癌的PSMA向辐射疗法,已经从LMICs中出现,特别是南非,印度和土耳其.

结论:

  • 无线电听器具有显著的潜力,可以改善LMICs的癌症诊断,治疗和监测.
  • 解决基础设施,教育和财务障碍对于扩大辐射卫生的使用是必不可少的.
  • 涉及国际组织,政府和私营部门的合作努力正在推动LMICs核医学能力的进步.