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Updated: Jul 7, 2026

Laser-assisted Microdissection LAM as a Tool for Transcriptional Profiling of Individual Cell Types
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Laser-assisted Microdissection LAM as a Tool for Transcriptional Profiling of Individual Cell Types

Published on: May 10, 2016

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对Hippeastrum物种的遗传洞察:一个比较的转录基因分析

Vaishali M Gopala1, Madhugiri Nageswara-Rao1, Rajanikanth Govindarajulu2

  • 1Subtropical Horticulture Research Station, USDA-ARS, 13601 Old Cutler Road, Miami, FL 33158, USA.

Journal of biosciences
|November 12, 2025
PubMed
概括

这项研究揭示了Hippeastrum的花特征的遗传基础. 香味基因在H. brasilianum中活跃,而色彩基因在H. papilio及其混合物中被上调.

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Published on: December 22, 2017

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A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq07:09

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq

Published on: May 28, 2021

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Gene Evolution - Fast or Slow?

The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
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The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
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Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...