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由于先天性腹膜的婴儿死亡率,美国2007-2021年
Ramesh Vidavalur1,2, Kanekal S Gautham3
1Division of Neonatology, Cayuga Medical Center, Ithaca, New York, USA.
Birth defects research
|November 12, 2025
概括
由于先天性隔膜 (CDH) 的婴儿死亡率在全国范围内正在下降,但仍然存在显著的地理和人口差异. 需要进一步努力,以确保所有患有CDH的婴儿获得公平的结果.
科学领域:
- 儿科健康 儿科健康
- 公共卫生监督 公共卫生监督
- 新生儿结局的结果.
背景情况:
- 先天性隔膜 (CDH) 是一种严重的出生缺陷,影响婴儿的生存.
- 了解CDH相关婴儿死亡率的时间和地理趋势对于公共卫生干预至关重要.
研究的目的:
- 分析美国与先天性隔膜 (CDH-IMR) 相关的婴儿死亡率的时间趋势和地理变化.
- 确定影响CDH-IMR的人口因素,并探索区域差异.
主要方法:
- 利用CDC-WONDER链接的2007-2021年出生/死亡数据来确定CDH相关的婴儿死亡 (ICD-10:Q79).
- 分析了使用结点回归的年度CDH-IMR趋势,并探索了与性别,性别,妊娠年龄 (GA) 和美国出生状态的关联.
- 计算了每10万活产婴儿的CDH-IMR,并进行了人口和区域比较的双变量分析.
主要成果:
- 在2007年至2021年期间,在超过590万活产婴儿中,共记录了3391例CDH相关的婴儿死亡.
- 整体CDH-IMR显示出明显的下降趋势 (APC: -1.3%).
- 在美国各州观察到CDH-IMR的显著变化 (三倍范围),亚洲婴儿的死亡风险较低,与高GA相关的生存率有所改善.
结论:
- 在美国观察到先天性腹膜婴儿死亡率 (CDH-IMR) 的下降趋势.
- 尽管总体下降,但基于地区,性别和种族的CDH死亡率仍然存在显著差异.
- 需要公平地改善护理,以应对不同的人口群体和地理位置的结果差异.
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