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全球评估乳腺癌风险与饮食摄入量之间的关系:一项生态研究
Najoua Lamchabbek1,2, Inge Huybrechts3, Imad El Badisy2
1Mohammed VI International School of Public Health, Mohammed VI University of Sciences and Health, Casablanca, Morocco.
American journal of health promotion : AJHP
|November 12, 2025
概括
全球饮食模式与乳腺癌 (BC) 风险有着复杂的关系. 该研究发现,酒精消费可能是全球BC发病率的重要风险因素.
科学领域:
- 流行病学 流行病学
- 营养科学 营养科学
- 在瘤学瘤学.
背景情况:
- 乳腺癌 (BC) 是一个主要的全球健康问题,发生率各不相同.
- 关于饮食和BC风险的现有研究主要使用个人级别的数据,缺乏全球生态视角.
- 需要对饮食和BC发病率进行全面的全球评估.
研究的目的:
- 在全球范围内描述和评估BC发病率与国家一级的食物和营养素摄入量之间的关系.
- 在全球范围内识别乳腺癌的潜在饮食风险因素.
主要方法:
- 使用公开可用的国家级数据进行生态研究设计.
- 数据来源于全球癌症观测站和全球饮食数据库,涵盖175个国家.
- 多变量线性回归分析以混因素进行调整,以评估饮食摄入量和BC发生率之间的关联.
主要成果:
- 最初的分析表明,几种食物/营养素与BC风险之间存在关联.
- 经过邦费罗尼校正后,大多数关联在统计学上并不显著.
- 酒精消费仍然与乳腺癌发病率有显著的积极联系 (β = 0.209,P = 0.048).
结论:
- 饮酒可能是乳腺癌的重要危险因素.
- 饮食因素和BC风险之间的关系是复杂的.
- 这些发现为未来对饮食和BC的个人水平研究提供了基线.
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