Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

7.1K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
7.1K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

4.9K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
4.9K
Regression Toward the Mean01:52

Regression Toward the Mean

6.8K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Correction: The association between RDW-to-platelet ratio and in-hospital mortality in critically ill stroke patients: A retrospective cohort study based on the eICU database.

PloS one·2026
Same author

Seed dispersal and recruitment limitation explain the alpine meadow species diversity loss due to nitrogen enrichment.

Proceedings. Biological sciences·2026
Same author

The association between RDW-to-platelet ratio and in-hospital mortality in critically ill stroke patients: A retrospective cohort study based on the eICU database.

PloS one·2026
Same author

Recurring marine phosphorus spikes during major palaeozoic mass extinctions and climate change.

Nature communications·2026
Same author

Phenological shifts compensated reproductive success due to nitrogen enrichment in an alpine meadow.

The New phytologist·2026
Same author

Advanced leaf emergence partially mitigated the negative effect of plant size on biomass under warming.

Ecological applications : a publication of the Ecological Society of America·2025

相关实验视频

Updated: Jan 11, 2026

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

1.0K

基于使用最大概率方法的真实数据,开发甲状腺激素的三个月特定参考间隔.

Xiaoyan Chen1, Yinrui Zou2, Yunxia Chu1

  • 1Department of Laboratory Medicine, Linyi Maternal and Child Healthcare Hospital, Luozhuang District, Linyi City 276016, Shandong Province, China.

Laboratory medicine
|November 12, 2025
PubMed
概括
此摘要是机器生成的。

通过使用现实世界的怀孕数据,为甲状腺刺激激素 (TSH) 和自由甲状腺素 (FT4) 建立了新的三个月特定的参考间隔. 这些从最大概率方法中得出的间隔,与现有指南相比,显示TSH的极限较窄.

关键词:
间接方法是间接的方法.最大的概率方法方法.参考时间间隔的参考时间间隔.三个月内特定的甲状腺激素.

更多相关视频

An Ex vivo Culture System to Study Thyroid Development
08:33

An Ex vivo Culture System to Study Thyroid Development

Published on: June 6, 2014

12.0K
Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
04:14

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Published on: October 6, 2023

1.2K

相关实验视频

Last Updated: Jan 11, 2026

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

1.0K
An Ex vivo Culture System to Study Thyroid Development
08:33

An Ex vivo Culture System to Study Thyroid Development

Published on: June 6, 2014

12.0K
Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
04:14

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Published on: October 6, 2023

1.2K

科学领域:

  • 内分泌学 在内分泌学.
  • 生殖医学 生殖医学
  • 临床化学 临床化学

背景情况:

  • 确立甲状腺激素准确的三个月特定的参考间隔对于在怀孕期间管理甲状腺功能障碍至关重要.
  • 现有的指导方针可能无法完全反映甲状腺刺激激素 (TSH) 和自由甲状腺素 (FT4) 水平的现实变化.

研究的目的:

  • 通过使用现实世界的数据,在孕妇中确定TSH和FT4的三个月特定的参考间隔.
  • 为了将这些新建立的间隔与现有的指南建议的间隔进行比较.

主要方法:

  • 利用了2014年7月至2019年12月的非识别妊娠数据,包括TSH,FT4和抗甲状腺过氧化酶抗体 (TPO-Ab).
  • 应用最大概率方法对TPO-Ab阴性怀孕在数据清理后确定参考间隔.
  • 在分析中包括超过55,000个怀孕记录.

主要成果:

  • 建立了TSH (例如,第一个三个月的0.40-4.09mIU/L) 和FT4 (例如,第一个三个月的12.2-20.5 pmol/L) 的三个月特定的参考间隔.
  • 最大概率方法衍生的FT4间隔与指导间隔相似,在第一和第二季度略有差异.
  • 使用最大概率方法计算的TSH参考间隔比当前指南所建议的更窄.

结论:

  • 在怀孕期间使用最大概率方法成功建立了TSH和FT4的三个月具体参考间隔.
  • 与现有指导方针相比,新的间隔没有显示FT4的临床显著差异,TSH的临床显著差异和更窄的极限.
  • 这些发现支持使用方法衍生间隔来更精确地评估怀孕期间的甲状腺功能.