在北美预先怀孕队列研究中,童年逆境和自发流产
Andrea S Kuriyama1, Sharonda M Lovett1, Amelia K Wesselink1
1Department of Epidemiology, Boston University School of Public Health, Boston, MA.
American journal of epidemiology
|November 12, 2025
概括
儿童时期的身体和性虐待可能会增加自发流产的风险,特别是在儿童时期社会支持较低的妇女身上. 这突显了早期生活经历对生殖健康结果的影响.
科学领域:
- 生殖健康 生殖健康
- 心理社会流行病学心理学
- 围产期研究 围产期研究
背景情况:
- 童年逆境与负面的成年健康结果有关.
- 童年逆境,社会支持和自发流产 (SAB) 风险之间的关系需要进一步调查.
研究的目的:
- 检查童年逆境和自发流产 (SAB) 风险之间的关联.
- 评估儿童社会支持和融入 (SSI) 对这一关联的潜在调节作用.
主要方法:
- 来自北美怀孕研究在线预设队伍的6100名参与者的分析.
- 使用不良童年经历 (ACE) 尺度和简要创伤问卷 (BTQ) 评估童年逆境.
- 使用伯克曼-西姆社会网络指数对终身社会支持和融入 (SSI) 的评估.
- 通过随访问卷跟踪怀孕结果;统计分析采用了Cox比例危险回归.
主要成果:
- 无论是ACE分数还是其个别领域都没有显示出与SAB风险的显著关联.
- 在BTQ上报告童年身体,性或两种类型的虐待与SAB风险略有增加有关.
- 这种关联在报告儿童早期SSI的参与者中显著更强,身体和性虐待的危险比率为1.76 (95%CI:1.15-2.68),与没有虐待相比.
结论:
- 儿童时期的身体和性虐待,特别是在BTQ评估时,可能与自发流产的风险增加有关.
- 较低的儿童社会支持和融入水平似乎加剧了童年虐待和SAB风险之间的联系.
- 这些发现强调了考虑到童年经历和社会支持在理解生殖健康结果的重要性.
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