潜伏类在儿童的长期功能状况的复发性危急疾病的孩子
Julia A Heneghan1, Kailash R Velusamy2, Sriram Ramgopal3
1Division of Pediatric Critical Care, University of Minnesota Masonic Children's Hospital, University of Minnesota, Minneapolis, MN.
Critical care medicine
|November 12, 2025
概括
研究人员在重复入院儿科重症监护室 (PICU) 的儿童中确定了六种不同的功能状态轨迹. 这些轨迹在稳定性和随时间变化方面各不相同,与各种临床和人口因素相关.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 健康研究成果研究结果
- 长度患者研究 长度患者研究
背景情况:
- 了解功能状态轨迹对于经常入住儿科重症监护室 (PICU) 的儿童至关重要.
- 以前的研究还没有完全描述这个脆弱人群中功能状态变化的多样化模式.
研究的目的:
- 识别和描述在经历多次PICU入院的儿童中功能状态的不同轨迹.
- 描述与每个已识别的功能状态轨迹相关的临床和人口因素.
主要方法:
- 在2017年4月至2022年12月期间,对美国24个儿科重症监护室 (PICU) 的数据进行了回顾性分析.
- 使用功能状态量表 (FSS) 来测量基线和PICU放出时的功能状态.
- 采用潜伏轨迹分析来识别FSS得分的截然不同的纵向模式 (类别) 在6038名儿童中, >1名PICU入院.
主要成果:
- 确定了六个潜在功能状态轨迹类别:三个稳定 (良好,中度,严重功能障碍),两个恶化,一个改善.
- 稳定的良好功能状态类别占该队列的46.6%.
- 轨迹类根据年龄,种族/种族,诊断,程序暴露,疾病严重程度和逗留时间有显著差异.
结论:
- 这项研究定义了在经常入院PICU的儿童中六种不同的功能状态结果轨迹.
- 这些轨迹呈现出独特的临床和人口特征,突出显示了患者的异质性.
- 调查结果强调了个性化评估和重复重症监护暴露儿童的管理的重要性.
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