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Updated: Jan 11, 2026

Tools to Study the Role of Architectural Protein HMGB1 in the Processing of Helix Distorting, Site-specific DNA Interstrand Crosslinks
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Published on: November 10, 2016

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通过将G-四重复向三重复结构转移,对c-Myc瘤基因表达的高度特异性抑制

Jolanta Lisowiec-Wąchnicka, Karolina Zielińska, Anna Pasternak

    Journal of medicinal chemistry
    |November 12, 2025
    PubMed
    概括

    新的折叠式三倍体形成寡核酸 (FTFOs) 精确地准瘤基因G-四倍体. 这种创新策略有效地减少了c-Myc的表达,并损害了癌细胞的生长,提供了一个有前途的抗癌疗法.

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