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药物诱导的间歇性肺病在肺癌患者中的肺癌患者

Gilles Vanhandsaeme¹, Karolien Viskens¹, Valerie Van Ballaer²

¹Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.

Respiration; international review of thoracic diseases

|November 12, 2025

概括

药物诱导的间歇性肺病 (D-ILD) 是肺癌治疗的罕见但严重的副作用. 早期识别和多学科方法对于管理这种具有挑战性的诊断至关重要.

科学领域:

肺部病理学肺部病理学
在瘤学瘤学.
药理学药理学是指药理学的学科.

背景情况:

肺毒性是系统性肺癌疗法的已知不良事件 (AE).
药物诱导的间歇性肺病 (D-ILD) 是一种罕见的,可能致命的肺AE.
D-ILD具有可变和非特异性的临床和放射性特征,使诊断复杂化.

研究的目的:

审查D-ILD的发病率,风险因素,临床和放射特征.
讨论肺癌患者D-ILD的管理策略.
为差异诊断提供一个框架,以帮助临床决策.

主要方法:

在肺癌全身治疗的背景下对D-ILD的文献综述.
讨论诊断挑战和多学科方法.
介绍了差异诊断的实用框架.

主要成果:

详细介绍了D-ILD发病率,危险因素和临床/放射性表现.
管理策略强调早期怀疑和综合护理.
建议采用差异诊断框架来协助临床医生.

结论:

有效的D-ILD管理需要高度的临床怀疑和患者/提供者教育.
迅速评估新的呼吸道症状或放射性异常至关重要.
D-ILD诊断是复杂的,通常是排除的诊断,受益于涉及肺病学家的多学科方法.

关键词:

药物诱导的间歇性肺病是药物引起的.肺癌是一种肺癌.放射学放射学是一门学科.系统性癌症治疗系统性癌症治疗

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