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Updated: Jan 11, 2026

Mining Spatial Transcriptomics Datasets using DeepSpaceDB
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Mining Spatial Transcriptomics Datasets using DeepSpaceDB

Published on: September 5, 2025

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一个统一的框架,用于在空间转录学研究中识别特定于细胞类型的空间可变基因.

Zhiwei Wang1, Yeqin Zeng1, Ziyue Tan1

  • 1Department of Mathematics, The Hong Kong University of Science and Technology, Hong Kong, China.

Proceedings of the National Academy of Sciences of the United States of America
|November 12, 2025
PubMed
概括

我们开发了混合模型混合 (MMM) 以在空间转录基因数据中识别细胞类型特定的空间变量基因 (SVG). MMM有效地揭示了与复杂的特征和组织微环境相关的SVG.

关键词:
复杂的特征和疾病.受到惩罚的准可能性.空间变量的基因瘤微环境是一个微环境.测试差异组件测试的差异组件测试

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