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Updated: Jan 11, 2026

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
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爱斯坦-巴尔病毒重编程自动反应性B细胞成为系统性红斑狼中的抗原呈现细胞

Shady Younis1,2, Salvinaz I Moutusy1,2, Sajede Rasouli1,2

  • 1Division of Immunology and Rheumatology, Stanford University, Stanford, CA 94305, USA.

Science translational medicine
|November 12, 2025
PubMed
概括

爱斯坦-巴尔病毒 (EBV) 感染在患有全身性红斑狼 (SLE) 的患者中重新编程自主反应性B细胞. 这些EBV阳性B细胞通过呈现自身抗原和激活T细胞来驱动自身免疫,促进SLE的发病.

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