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Updated: Jan 11, 2026

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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人类分离酶的基质识别

Jun Yu1, Sophia Schmidt1, Margherita Botto1

  • 1Department of Molecular and Cellular Biology, University of Geneva, Geneva, Switzerland.

Science advances
|November 12, 2025
PubMed
概括

人类分离酶在细胞分裂过程中分裂SCC1/RAD21凝聚素子单元以分离姐妹染色体. 这项研究揭示了分离酶如何识别和分裂SCC1,阐明了线粒分裂的一个关键机制.

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