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Updated: Jan 11, 2026

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在HIV-1组装过程中逃避CARD8激活

Ivy K Hughes1, James B Hood1, Andrés A Quiñones-Molina1

  • 1Department of Virology, Immunology, & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.

Science advances
|November 12, 2025
PubMed
概括

人类免疫缺陷病毒1型 (HIV-1) 组合蛋白 Gag 控制病毒蛋白酶活性,以防止 CARD8.8 进行免疫传感. 这种机制增强了受感染的CD4+T细胞的存活率和病毒适应性.

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