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Updated: Jan 11, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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从四醇到异类:基于结构的优化和AR-C118925衍生的P2Y2受体对抗剂的晚期多样化

Rayan Aboalgasim Makawi Abdalrahman1, Katja Schlegel2, Victor Hugo Catricala Fernandes3

  • 1University of Tuebingen, Department of Preclinical Imaging and Radiopharmacy, Cluster of Excellence iFIT (EXC 2180) "Image-guided and Functionally Instructed Tumor Therapies", Roentgenweg 13, 72076, Tuebingen, Germany.

European journal of medicinal chemistry
|November 12, 2025
PubMed
概括

研究人员开发了新的P2Y2受体对手来治疗癌症和炎症性疾病. 新化合物显示出更好的选择性和功效,为药物开发提供了一个有希望的支架.

关键词:
在AR-C11892525中使用.敌对者的敌对者生物异构体 生物异构体后期阶段的多样化多样化.P2Y(2) 受体受体的使用情况.结构与活动之间的关系.

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