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Updated: Jan 11, 2026

Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro
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矩阵刚性的机制通过调节Piezo1来影响形大动脉膜疾病

Naifang Cao1, Si Cheng1, Haochang Hu1

  • 1Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, 310009, Hangzhou, PR China; State Key Laboratory of Transvascular Implantation Devices, 310009, Hangzhou, PR China; Heart Regeneration and Repair Key Laboratory of Zhejiang Province, Hangzhou, 310009, PR China.

Atherosclerosis
|November 12, 2025
PubMed
概括

在性大动脉病 (CAVD) 中细胞外矩阵刚度的增加可提高Piezo1. 在膜间歇细胞 (VICs) 中抑制Piezo1抑制骨质分化和ECM重塑,这表明CAVD的治疗点.

关键词:
在CAVD中,它是最重要的.进行ECM重建.矩阵的刚度 矩阵的刚度骨质变异的分化 骨质变异的分化这是一个Piezo1.

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