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Updated: Jan 11, 2026

A Multimodal Wide-Field Fourier-Transform Raman Microscope
06:48

A Multimodal Wide-Field Fourier-Transform Raman Microscope

Published on: December 30, 2025

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探索多变量曲线分辨率-交替最小正方形 (MCR-ALS) 的探索,以采集动态演变的复杂细胞光谱数据 (光谱学)

Nitin Patil1, Zohreh Mirveis1, Hugh J Byrne2

  • 1FOCAS Research Institute, TU Dublin, City Campus, Camden Row, Dublin 8, Ireland; School of Physics, Optometric and Clinical Sciences, TU Dublin, City Campus, Grangegorman, Dublin 7, Ireland.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
|November 12, 2025
PubMed
概括

这项研究探索了多变量曲线分辨率-交替最小平方 (MCR-ALS) 分析细胞拉曼光谱数据. 虽然MCR-ALS在定量准确性方面存在局限性,但使用MCR初步估计和ALS动态约束的定性方法有效地揭示了代谢过程指纹.

关键词:
细胞代谢动力学多变量曲线分辨率-交替最小平方.拉曼光谱法 拉曼光谱法 拉曼光谱法频谱学是一种光谱学.

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