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Updated: Jan 11, 2026

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快速的细胞周转以模拟脂肪细胞大小分布.

Louis Fostier1, Aloïs Dauger2, Romain Yvinec1

  • 1PRC, INRAE, CNRS, Université de Tours, Nouzilly, 37380, France; Université Paris-Saclay, Inria, Centre Inria de Saclay, Palaiseau, 91120, France.

Journal of theoretical biology
|November 12, 2025
PubMed
概括

白色脂肪组织脂肪细胞的大小分布是双模的. 一个使用部分微分方程的新型动态模型解释了这一点,只需要三个参数才能在老鼠中准确地表征.

关键词:
脂肪细胞的大小分布参数估计的参数估计.部分微分方程建模部分微分方程静止溶液是一种静止溶液.白色脂肪细胞组织组织.

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Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...
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