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在不可切除和可切除肝脏瘤中,肝动脉输液治疗

Lauren M Janczewski¹, Ryan P Merkow²

¹Department of Surgery, Northwestern University Feinberg School of Medicine, 676 North St. Clair Street, Arkes Suite 650, Chicago, IL 60611, USA.

Hematology/oncology clinics of North America

|November 12, 2025

概括

肝动脉输液 (HAI) 化疗提供高剂量治疗直接到肝脏瘤,最大限度地减少全身毒性. 这种区域疗法越来越多地用于各种肝癌,特别是不可切除的肝癌.

科学领域:

在瘤学瘤学.
肝胆道医学肝胆道医学
癌症治疗方法癌症治疗方法

背景情况:

肝动脉输液化疗 (HAI) 是针对肝脏恶性瘤的向性静脉内治疗.
它利用肝脏瘤通过肝动脉的主要血液供应.
这种方法增强了药物输送,同时减少了全身副作用.

研究的目的:

描述HAI化疗的原理和应用.
为了突出其在治疗各种肝脏恶性瘤中的不断扩大的作用.
为了强调其在不可切除的肝癌病例中的使用.

主要方法:

高剂量的floxuridine直接输入肝动脉.
利用肝脏的第一通取机制来集中化疗.
在患有结直肠肝转移,肝内胆管癌和肝细胞癌的患者中应用.

主要成果:

高度的药物度直接在肝脏瘤中实现.
与传统化疗相比,降低了全身毒性.
有效的区域治疗不可切除的肝脏恶性瘤.

结论:

HAI化疗为治疗肝癌提供了一种有效的策略.
它的应用范围正在扩大,超越结直肠转移到其他主要肝脏瘤.
它是管理不可切除的肝脏恶性瘤的关键选择.

关键词:

胆道硬化是一种胆道硬化.胆性瘤是一种胆性瘤.结肠直肠肝转移的发生.输入肝动脉的输液.

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