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Updated: Jan 11, 2026

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease
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针对阿尔茨海默氏症的APOE向治疗方法

Hussein N Yassine1,2, Cristelle Hugo3, Bernadette O'Donovan4

  • 1Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033 hyassine@usc.edu o.chibafalek@duke.edu.

The Journal of neuroscience : the official journal of the Society for Neuroscience
|November 12, 2025
PubMed
概括

脂蛋白E (APOE) 对于大脑脂质运输至关重要. APOE4变种破坏了这一点,通过脂质失衡,炎症和神经元功能障碍增加了阿尔茨海默病的风险.

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