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Updated: Jan 11, 2026

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YTHDF2调节自我非编码RNA代谢,以控制炎症和瘤发生

Seungwon Yang1, Yan-Hong Cui2, Haixia Li2

  • 1Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA. syang80research@gmail.com.

Nature communications
|November 12, 2025
PubMed
概括

YTHDF2识别了m6A甲基化U6snRNA,降低了它的稳定性并阻止了Toll-like受体3 (TLR3) 的激活. 这种机制抑制炎症和瘤发生,突出显示YTHDF2和m6A U6作为治疗点.

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